Screening of Risk Phenotypes Among Metabolic Syndrome Subjects in Adult Pakistani Population

Abstract

Background

Metabolic Syndrome is a clustering of multiple risk factors including central obesity, hypertension, dyslipidemia and hyperglycemia. These risk phenotypes of metabolic syndrome (MetS) prevalent world-wide, Therefore, we aimed to identify the frequency of risk phenotypes among metabolic syndrome subjects in local adult Pakistani population.

Methodology:

Screening of subjects visiting out-patient department of medicine, Pakistan Institute of Medical Sciences, Islamabad was performed to assess the occurrence of risk phenotypes among MetS subjects in Pakistani population. The Metabolic Syndrome was defined based on International Diabetes Federation (IDF) criteria. Anthropometric and biochemical assay results were recorded. Data was analyzed using SPSS software (16.0).

Results

Our results showed that dyslipidemia (31.50%) and hyperglycemia (30.50%) was most population specific risk phenotypes of MetS. The results showed the order of association of metabolic risk phenotypes to MetS as follows hyperglycemia>dyslipidemia>obesity >hypertension.

Conclusion

The hyperglycemia and dyslipidemia were found be the major risk phenotypes among the MetS subjects and have greater chances of developing MetS among Pakistani Population.

Key Words: Metabolic syndrome, Hypertention, Dyslipidemia, Obesity, MetS