Frequency of CRP levels in patients presenting with Acute Coronary Syndrome

Abstract

Objective: To evaluate the prognostic value of C-reactive protein (CRP) in predicting cardiovascular outcomes in patients presenting with acute coronary syndrome (ACS).

Methodology: This cross-sectional study was conducted in the Department of Cardiology, KRL Hospital, Islamabad, from Oct 2021 to March 2022. A total of 117 patients of both gender having age between 40 to 80 years, presenting with chest pain were included in the study.  Data were analyzed on SPSS version 25. Chi square test was used to compare outcomes of both groups. Brief history of demographic information and written informed consent was taken from each patient. The findings of quantitative variables and qualitative variables were entered in study’s questionnaire. Effect modifiers were controlled through stratification of age, gender. P-value of 0.05 considered statistically significant.

Results: There were a total of 117 patients enrolled in this study. Among them there were 63 (53.85%) males, and 79 (67.52%) were above 60 years of age. There were 90(76.92%) patients who had a raised CRP level, and 78 (66.67%) had duration of ACS > 12 hours. Differences between duration of elevated CRP and non-elevated CRP was statistically significant (p value = 0.013).

Conclusions:  CRP levels may be indicative of suspected acute coronary syndrome. Physicians can identify such patients and provide them with more intensive health care and cardiac management. Resources are scarce in the developing world. Having such tools that are more economical can help with the diagnosis and provide better care.